As Nathan just said, a lot of the fluidity we enjoyed in the first half has gone out of the game now.

10 minutes to go as Cambridge make their first switches.

Louis Appere is replaced by Shayne Lavery and Sullay Kaikai comes on for goalscorer Ben Knight.

Nathan Thompson
Former Swindon player

I felt that Cambridge's intensity wouldn't last and they'd feel the pressure as we head towards full-time.

But they're still being very dominant and have brought an assured performance.

Image source, Shutterstock

Wigan and Leyton Orient boss a half each but neither make their mark on the scoreline to share the points.

After Wigan offered more threat in the first half, Orient took their turn in the second but like their hosts couldn't make any of their chances count.

Two more changes for Swindon, their final ones of the evening.

Ollie Palmer and Fletcher Holman are off, Michael Olakigbe and James Scanlon come on with 74 minutes on the clock.

Nathan Ellington
Ex-Wigan Athletic striker on BBC Radio Manchester

I think Wigan will be happy to end up with a point after the second half.

Tickle's had a few saves, Wigan haven't got into the flow of things and I think they'll be happy with a point now.

Or maybe they can get something in the last couple of minutes from one last attack.

Leyton Orient have been more in control this half but Wigan almost made them sore as Caylan Vickers lets loose.

It's spinning at lightning speed but wanders north of the net to leave the home supporters with their hands on their heads.

Four minutes added to the clock.

Nathan Thompson
Former Swindon player

You'll slowly start to see that it's so difficult for Cambridge to maintain the energy they've had for the past 70 minutes through the full 90, so they will drop off.

James Morris thrashes a cross across goal, begging for a man in red to guide it in but none of his Orient team-mates react in time.

Wigan respond by throwing the dice. They introduce striker Christian Saydee for midfielder Matt Smith.

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Not only do Cambridge have the best defensive record in England, they're unbeaten at home in 15 league matches.

It's a tough ask for Swindon as the game enters the final 20 minutes.

Josh Watton
BBC Radio Manchester commentator

Latics fans are trying to push their side over the line. A goal for either side would seal it.

Both sides have been on top but neither side has managed to make it count on the scoreboard.

Orient's Demetri Mitchell takes some treatment on the pitch but as soon as he's back on his feet, he's being switched out for Sonny Perkins.

Time running out. Enough for a match winner though.

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A reminder that Cambridge have only conceded 29 times this season.

That's the best record in the whole of the EFL.

Swindon have scored in every game since 26 December.

Is tonight when that run ends? They've got 25 minutes to do something.

Nathan Ellington
Ex-Wigan Athletic striker on BBC Radio Manchester

Orient are looking like they're probing and probing and probing to get a goal.

Now with these substitutes it's about whether Wigan can wrestle back control.

A double change for Wigan as momentum appears to swing Orient's way.

Caylan Vickers and Joseph Hungbo are on to replace Dara Costelloe and Raphael Borges Rodrigues.

Can they make a difference?

Swindon boss Ian Holloway makes three changes just before the hour mark.

OFF: Will Wright, Gavin Kilkenny, Tom Nichols

ON: Aidan Borland, Billy Bodin, Joel McGregor

Wigan keeper Sam Tickle is having to earn his pay at the moment.

Demetri Mitchell swipes at goal from distance and it's awkward for the stopper but Tickle dives to provide yet another save.

That's shot number five on target for the visitors.

The hosts? Nada thus far.

There's definitely a lull hitting the Brick Community Stadium but once you see Dom Ballard on the ball inside the box, you know things will liven up fast.

He evades the defenders, opening up a path to goal but Wigan keeper Sam Tickle is there to jump up and get his gloves to it.

It's a fine save by Swindon stopper Connor Ripley but it really should be 2-0.

Ben Knight jigs his way into the box, via a couple of deflections off defenders, and is suddenly clean through on goal.

He tries to slot it low to Ripley's left, but the keeper diverts the ball wide with his knee.

Nathan Ellington
Ex-Wigan Athletic striker on BBC Radio Manchester

There hasn't been a lot of urgency in the last 15 minutes. Wigan aren't asking questions of Orient.

Both teams currently not showing much quality on the field which is why we're not seeing the end product.