Davante Adams scores hat-trick for Rams
Chiefs demolish Raiders and Eagles see off strong Vikings challenge to move to 5-2 in early games
Colts beat Chargers 38-24 to move to 6-1
Broncos pull off thrilling comeback from 19-0 down to beat Giants with last kick of game
Indianapolis Colts @ Los Angeles Chargers (21:05 BST)
BBC Radio 5 Sports Extra
The Colts own the joint-best record in the league, the Chargers have a sound defence when healthy and a head coach in Jim Harbugh who is building something.
So it's a big prove-it game for Indianapolis, and you can listen to live radio commentary on BBC Radio 5 Sports Extra right here or via the icon at the top of the page.
Indianapolis Colts @ Los Angeles Chargers (21:05)
Image source, Getty ImagesThe Colts had the joint-best record in the league at 5-1 and they're outright leaders in the scoring charts, going at a fine 32.3 points per game so far.
Daniel Jones is reborn in Indy, with five games out of six with a passer rating of 100 or higher, while he's just the third QB ever to score a passing and rushing touchdown and have a 100+ passer rating in three of the opening six games of a season.
Having the NFL's leading rusher in Jonathan Taylor (603 yards) helps this balanced but potent Colts attack.
The 4-2 Chargers are a tough outfit though under Jim Harbaugh, even though they'd struggled with injuries they got back to winning ways last week out in Miami and Justin Herbert looks in decent touch.
A tough one to call this one.
We're kicking off in the late games too!
Previews coming shortly!
Miami Dolphins 6-31 Cleveland Browns
Image source, Getty ImagesI suspect there will be a fair bit of talk about coaching changes in Miami this week.
The Dolphins were attrocious and are now 1-6 for the season.
Cleveland have a fantastic defence anyway, but they were helped out by three Tua Tagovailoa interceptions, meaning his opposing quarterback Dillon Gabriel had to do very little in his second start.
Fellow Browns rookie Qunishon Judkins had a hat-trick of touchdowns as he continues to impress.
New Orleans Saints 14-26 Chicago Bears
Image source, Getty ImagesIt looked like it would be a simple day for the Bears as they surged to a 20-0 lead but New Orleans would not lie down - two Chris Olave touchdowns made a game of it.
Ultimately it was decided by Chicago's superior rushing attack - 222 yards to 44 - and Spencer Rattler's three interceptions.
He'd only thrown one all season before today.
The Bears have now won four in a row and have momentum in a stacked NFC North.
Philadelphia Eagles 28–22 Minnesota Vikings
Another bomb from Jalen Hurts!
This one connects with AJ Brown 45 yards down the field and supplies a dagger to the hopes of Minnesota.
Philadelphia Eagles 28-22 Minnesota Vikings
What do I know?
Will Reichard has bumped his kick down the field and backed the defence to get the ball back for the Vikings.
Philadelphia Eagles 28–22 Minnesota Vikings
A fifth successful field goal of the day for Will Reichard makes this a one-possession game.
It's all about the on-side kick now for Minnesota Vikings.
Philadelphia Eagles 28–19 Minnesota Vikings
Not the time to take a sack.
Carson Wentz is dumped to the ground by this Philly defence and it's now a more daunting task with eight extra yards tagged on.
He connects with TJ Hockenson on the next play but it's not enough for a first down.
Facing fourth and 11 as we go to the two-minute warning.
Philadelphia Eagles 28–19 Minnesota Vikings
Gutsy from the Vikings as Carson Wentz connects with Jordan Addison.
They'll get a fresh set of downs with 10 yards to go.
Philadelphia Eagles 28–19 Minnesota Vikings
Heartbreak for Minnesota.
TJ Hockenson's catch is chalked off with the review ruling the ball hit the ground before he had full control.
They're facing fourth and two.
Carolina Panthers 13-6 New York Jets
The Jets finally find some success.
Nick Folk converts a 47-yard field goal.
New Orleans Saints 14-26 Chicago Bears
That might just be the game. Spencer Rattler's risky pass down the centre of the field is tipped and then picked off by Tremaine Edmunds.
A third interception of the day for the New Orleans QB.
Philadelphia Eagles 28–25 Minnesota Vikings
Terrific from Carson Wentz as he scrambles to the right before launching a dart into the end zone.
There's his tight end TJ Hockenson taking air to catch it.
Ruling on the field is a touchdown but did it hit the floor...?
FT: Las Vegas Raiders 0–31 Kansas City Chiefs
Image source, Getty ImagesKansas City put a divisional rival in their place with a brutally efficient display against Las Vegas Raiders.
After a year out through injury and a six-match NFL suspension, Rashee Rice scored two touchdowns as the Chiefs got seven points on each of their first four drives.
The home team move to 4-2 and Patrick Mahomes was rested for the fourth quarter.
Offensive stats: Raiders 95 yards v 434 yards for Chiefs
New Orleans Saints 14-26 Chicago Bears
Jake Moody boots his third field goal of the day to put more daylight between his Bears and New Orleans.
Bears heading for their fourth-straight win.
Philadelphia Eagles 28–19 Minnesota Vikings
Nice hip swivels from Vikings quarterback Carson Wentz as he bamboozles tacklers not once, but twice to pick up 16 yards.
They're into Philadelphia territory but need two scores.
Las Vegas Raiders 0–31 Kansas City Chiefs
With Patrick Mahomes cheerfully watching from the sidelines, Raiders counterpart Geno Smith has also been taken out of the game.
It's the battle of the back-ups in Gardner Minshew v Kenny Pickett.
But this game is done.
Philadelphia Eagles 28–19 Minnesota Vikings
Image source, Getty ImagesClinical.
A 26-yard pass from Jalen Hurts is clasped by AJ Brown and he secures his second touchdown of the day.
Eagles offence humming, perhaps for the first time this season.
Miami Dolphins 6-31 Cleveland Browns
This is getting silly. Second pass of their next drive and Tua has thrown another interception, his third of the day.
He's all over the place. Ronnie Hickman picks him off this time and Cleveland have the ball in Miami's half.