Jasper Wiese, Cobus Reinach and Jesse Kriel cross for the hosts in a one-sided first half
Jaco Williams scores the try bonus-point straight after the break before Herschel Jantjies, Kurt-Lee Arendse and Paul de Villiers add their names to South Africa's scoreboard
Wales' task made harder with Ben Warren's yellow card
Wales nilled by the Springboks for a second time this season after last autumn's 73-0 hammering
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South Africa v Wales (16:40 BST)
Jonathan Davies
Former Wales and British & Irish Lions centre on S4C
For me, Eddie James' best position is inside centre because they will need to be more physical and compact.
I'm shocked at the centre partnership and I hope they play well, but for me I want to see Eddie James playing more and getting more comfortable at the highest level.
South Africa v Wales (16:40 BST)
Image source, Huw Evans Picture AgencyThe teams are out and there is some tremendous miming of Wales' anthem.
In a few minutes Wales will need to shore up their defence if they are to keep things respectable in Durban.
Steve Tandy brought in Peter Murchie this summer as his defence coach, but it's been a tough start against Fiji and Argentina.
The Fijians dominated the first half in Cardiff before Wales turned the screw with their tight game while the Pumas won the battle of the gain line.
Fiji made 674 metres from 167 carries, racked up 32 offloads and had a whopping 24 clean breaks, beating 42 defenders.
Wales’ tackle success was just 64% in the first fixture as they missed 42 tackles.
That crept up to 81% in Argentina but there were still 31 misses.
The Pumas made 15 clean breaks and beat 31 defenders.
They didn't make as many offloads because they didn't need to with their brutal running that made 518 metres from 162 carries.
South Africa v Wales (16:40 BST)
Image source, Getty ImagesSouth Africa's demolition job in Cardiff finished on a sour note after Eben Etzebeth was red-carded.
The legendary lock was given a 12-week ban in December after an independent disciplinary panel found him guilty of an eye gouge on Alex Mann in the 79th minute.
The two-time World Cup winner later posted a video of the incident, claiming his actions were a reaction to being struck by the flanker and that the gouge was not intentional.
Cardiff's Mann, 24, was cleared of any wrongdoing in the incident.
"It's in the past now," he said in January. "A bit of handbags - everyone could see what happened. I've moved on and I'm just looking forward to what's next."
What was next for Mann was a superb Six Nations campaign and the flanker is back in the starting line-up in Durban.
He won't be going up against Etzebeth, who is sidelined during the Nations Championship because of concussion symptoms.
South Africa v Wales (16:40 BST)
Ken Owens
Former Wales hooker on S4C
Games like this will help show how strong the squad is and help us see how close a group they are and the culture they are building.
Nobody expects them to win but we will see what the character is like in the squad and the way they conduct themselves on the pitch.
South Africa v Wales (16:40 BST)
Image source, Huw Evans Picture AgencyIt's a year to the day that Steve Tandy had his final game as Scotland's defence coach, a 41-12 win against Samoa in Auckland.
He left that role to become Wales head coach and the fixture in Durban is his 13th (including the uncapped game against Barbarians) with a record of four wins and nine defeats
South Africa v Wales (16:40 BST)
Image source, Getty ImagesThe last time the teams met was in Cardiff in November, when Wales were stretched to the limit.
The fixture was played outside World Rugby's Test window and that meant the members of Steve Tandy's squad that played in England and France returned to their clubs.
The result was horrendous with South Africa - who were not full strength themselves - running wild at Principality Stadium.
The world champions scored 11 tries when dishing out the second worst defeat in Welsh rugby history after the 96-13 hammering by the Springboks in Pretoria in 1998.
The 73-0 defeat was a new low for Wales, who then suffered heavy defeats by England and France at the start of the Six Nations.
Things have got better since and there are some promising signs after a season under Tandy's management team, but this will be another stern challenge.
South Africa v Wales (16:40 BST)
James Hook
Former Wales fly-half on BBC Radio Wales
The one thing that the Nations Championship gives you is competition.
When I won my first cap on a summer tour to Argentina there was a lot of first class players rested, but now there is competition and you're more reluctant to rest your best players.
South Africa v Wales (16:40 BST)
Image source, Getty ImagesWales were overpowered by Argentina last week but things go up a notch against the Springboks.
South Africans always love a confrontation and it promises to be brutal on the gain line.
"I said post-match in San Juan that we were not physical enough and didn’t win those physical encounters," said Wales captain Dewi Lake.
“This weekend we will have to. If we are not at the races physically then it could get out of hand.
“It’s about being physical, winning collisions and going there to make a statement.”
The hits will be huge.
South Africa v Wales (1640 BST)
Dafydd Jones
BBC Sport Wales, Kings Park Stadium
The atmosphere around Kings Park has been building for hours, with Springbok supporters gathering outside the stadium around braais and soaking up the sunshine before kick-off.
Green and gold shirts dominate the area surrounding the ground, with an air of expectation among the home crowd.
Around 50,000 supporters are expected inside the stadium, creating one of international rugby's most iconic matchday atmospheres.
Wales know they'll need to cope not only with the Springboks, but also the noise that will greet them when they run out.
South Africa v Wales (16:40 BST)
Image source, Huw Evans Picture AgencyWales gave an international debut to Exeter flanker Kane James last week in Argentina and they provide more evidence of the back-row options in Durban by recalling Tommy Reffell.
The scavenging Leicester flanker was left out of Steve Tandy's squads for the autumn and Six Nations but returned for the summer tour.
Reffell will win his 30th cap off the bench against the Springboks and his first since facing Japan last summer.
The open-side started when Wales stunned South Africa in Bloemfontein four years ago, slotting into the back row with Dan Lydiate and Taulupe Faletau.
This time Reffell will be charged with having an impact at the breakdown off the bench when backing up Alex Mann, Jac Morgan and Aaron Wainwright along with fellow back-rower James Botham.
South Africa v Wales (16:40 BST)
Image source, Huw Evans Picture AgencyDewi Lake is fit to lead from the front for Wales after limping off in Argentina last weekend.
The hooker captains a side featuring six changes from San Juan.
In comes wing Louis Rees-Zammit, centres Ben Thomas and Max Llewellyn, fly-half Dan Edwards, lock Teddy Williams and flanker Alex Mann.
Rees-Zammit was meant to be coming in for Ellis Mee but instead it is for Josh Adams, who was a late withdrawal because of a tight calf.
Steve Tandy goes for six forwards on the bench, including Gloucester lock Freddie Thomas after he flew out to South Africa when Ben Carter suffered an ankle injury in training on Wednesday.
Wales: Murray; Rees-Zammit, Llewellyn, B Thomas, Mee; Edwards, Tomos Williams; Carre, Lake (capt), D Lewis, Teddy Williams, Beard, Mann, J Morgan, Wainwright
Replacements: Elias, N Smith, Warren, F Thomas, Reffell, Botham, Morgan-Williams, Hawkins.
South Africa v Wales (16:40 BST)
Image source, Getty ImagesRassie Erasmus has showed off the Springboks' remarkable depth in the Nations Championship and tinkers again after their win against Scotland.
The world champions make 10 changes to the starting line-up and include four uncapped players.
Wing Jaco Williams, fly-half Vusi Moyo, lock Ruben van Heerden and prop Carlu Sadie all make their Test debuts in Durban.
The Boks' side, captained by formidable flanker Pieter-Steph du Toit, is still packed with familiar names and the bench is stacked.
It's frankly scary to see a South Africa line-up like this and know they have the likes of Siya Kolisi, Cheslin Kolbe, Thomas du Toit, Eben Etzebeth, Franco Mostert, Andre Esterhuizen, Canan Moodie, Handre Pollard and Ox Nche on the sidelines.
South Africa: Fassi; Williams, Kriel, de Allende, Arendse; Moyo, Reinach; Steenekamp, Marx, Sadie, C Wiese, van Heerden, de Villiers, PS du Toit (capt), J Wiese
Replacements: Venter, Wessels, Louw, Dixon, van Staden, Jantjies, Libbok, Willemse.
South Africa v Wales (16:40 BST)
Image source, Huw Evans Picture AgencyGood afternoon and welcome to the coverage of Wales' final game of 2025-26 in Durban.
Steve Tandy was appointed as head coach of his country last summer and this will be his 13th fixture, and what a daunting one it is.
South Africa are two from two in the Nations Championship after swatting England aside and then edging out a spirited Scotland.
Wales travel to face the world champions after being handed a reality check by Argentina last weekend.
What would be a success for Tandy's side at Kings Park? Staying competitive? Let us know by using the yellow button on this page.
Anyway, let's have a look at the teams...
