Alyssa D'Inca (twice), Vittoria Zanette (twice) and Aura Muzzo score in first half for Italy, seeking first win of Six Nations campaign
Vittoria Vecchini adds to Italy's lead with sixth try
Hosts reduced to 13 players as Veronica Madia and Elisa Giordano are sent to sin-bin
Scotland take advantage to score through Lana Skeldon - but Italy add a try themselves through Giordana Duca while still two players down
Molly Poolman darts through to score Scotland's second try
Scotland captain Rachel Malcolm ruled out just before kick-off through injury
Italy 10-0 Scotland
Danielle Waterman
Former England international on BBC iPlayer
Scotland have to be careful that they don't play this open game that the Italians want. They are very comfortable. You need someone to be stepping up and organising.
Image source, Getty ImagesItaly 10-0 Scotland
It's a bit messy from Scotland, a hacked clearance not gaining anything as Italy then kick a penalty to touch.
Italy's Alissa Ranuccini is stopped short of the line, it looks like there might have been head onto head, but Scotland get a scrum just five metres from their own line.
Italy 10-0 Scotland
Andy Burke
BBC Sport Scotland Senior Reporter
Perhaps the loss of captain Rachel Malcolm before kick-off has knocked the Scottish confidence because they really have failed to come out the blocks.
They will need to get it together or else this game could go away from them very quickly.
Italy 10-0 Scotland
Danielle Waterman
Former England international on BBC iPlayer
She's been brilliant around the park so far Zanette, so to get that try was superb. That pick and go was way too easy, they didn't defend the blindside.
Image source, Getty Images
Vittoria Zanette
Italy kick to touch, then rumble from the lineout until Sofia Stefan tries to dart in. The scrum half is stopped short, but prop Vittoria Zanette follows up and crashes over top score on her first start.
The conversion goes awry, Veronica Madia running out of time before the shot clock expires.
Italy 5-0 Scotland
Scotland win their scrum, and bravely run it out with Lucia Scott heading towards halfway until scragged. Rollie then tries to run it back until stopped dead in her tracks by a crunching tackle from Veronica Madia.
Italy 5-0 Scotland
Italy pump a kick almost to the right hand corner, and Chloe Rollie's clearance is only just beyond the 22.
The hosts go right again with Aura Muzzo punching a hole in the Scottish defence, then Sofia Stefan takes to 10 metres out.
Italy 5-0 Scotland
Danielle Waterman
Former England international on BBC iPlayer
The Italians look energised in attack, and they are lethal out wide. Scotland look a little shell-shocked.
Italy 5-0 Scotland
It's been a slow start by Scotland, they need to camp out in the Italian half.
Italy 5-0 Scotland
Danielle Waterman
Former England international on BBC iPlayer
That's a phenomenal try. It shows just how Italy can catch the Scottish napping by going quickly.
Alyssa D'Inca
Image source, Getty ImagesItaly move it to the right through four pairs of hands umntil Alyssa D'Inca receives it, and the number 11 has just enough room to touch down just inside the corner flag.
Sublime stuff from the hosts.
Italy 0-0 Scotland
Scotland spin it wide from the scrum, full-back Chloe Rollie making a few metres towards halfway.
Scotland kick deep and Italy run it back, running a tap penalty which Vittoria Ostuni Minuzzi capitalises on to just short of the line
Italy 0-0 Scotland
Italy move the ball to the right, but winger Alyssa D'Inca can't hang on to a pass just ahead of her to give Scotland a scrum just outside their own 22.
Italy 0-0 Scotland
Scotland pin the Italians back in the first few seconds without threatening, fly-half Helen Nelson then kicks to touch on the Italy 22.
The hosts hoof it clear from the lineout, then prop Vittoria Zanette's rampaging run pushes the Scots back to their own 22.
Italy 0-0 Scotland
And we are off, with Scotland kicking off, the hosts in their dark blue and Scotland in a natty lilac kit.
Italy v Scotland (16:30)
Andy Burke
BBC Sport Scotland Senior Reporter
A big blow for Scotland as captain Rachel Malcolm is ruled out shortly before kick-off through injury. She's replaced in the back-row by Alex Stewart who goes in at 7, with Rachel McLachlan shifting to number eight. Becky Boyd comes onto the bench.
It will be very interesting to see how the Scots bounce back from that humbling at the hands of England last weekend.
Italy v Scotland (16:30 BST)
The teams are out, lead by Silvia Turani - below - on the occasion of her 50th cap for the Azzuri.
We're about to have the national anthems but there is also a moment of silence in memory of Gianfranco Ermoli, Italy Women's Coach from 2007 to 2009.
Image source, PA MediaItaly v Scotland (16:30 BST)
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Italy v Scotland (16:30 BST)
Scotland should have happy memories of this ground, having won 17-10 here two years ago. But it was Italy who had the upper hand in 2025, leaving Edinburgh with a 25-17 victory in their pockets.
Italy v Scotland (16:30 BST)
Scotland have made five changes to the side who were overwhelmed by England last Saturday.
Prop Demi Swan will make her first start, having appeared from the bench in the opening win in Wales and the defeat by England, and Eva Donaldson and Rachel McLachlan are also included in an overhauled back row.
Outside centre Lucia Scott and wing Francesca McGhie are also recalled among the backs, with the former making her first international start and the latter in the XV under head coach Sione Fukofuka for the first time after injury.
Rhona Lloyd and Emily Coubrough will not be involved because of concussion protocols, while Evie Wills has an arm problem.
