Charles Ollivon adds third try six minutes before half-time to give France 22-0 lead at break.
First time Ireland have been held to zero points in first half since 2020 and Bielle-Biarrey secures France four-try bonus point seven minutes after restart.
Donncha O'Callaghan Former Ireland lock on BBC Radio 5 Live at the Stade de France
That was incredible and it shows these kind of players just slight on space and when someone gets there hands free, they can put them into a hole. They are lethal when they get a ball like that.
Tommy O'Brien and Louis Bielle-Biarey have a great first contest in the air and it's the French wing, who lit up last year's tournament, who comes out on top this time.
The players emerge from the bright lights of the tunnel to the darkness of the Stade de France, which is only illuminated by the odd strobe light and flames.
Chris Ashton Former England wing on BBC Radio 5 Live at the Stade de France
Because Dupont is such a great player we all expect him to just pick straight up where he left off but he's not quite done that for Toulouse. There has been both sides of it and tonight, I am sure he can put on a performance that the world is expecting to see.