Jhon Duran's first Premier League goal since September allowed Aston Villa to make it back-to-back wins and piled further misery on Southampton.
The Colombian striker is usually used as a substitute but scored on what was his first league start of the season to lift Villa to fifth.
Unai Emery's Villa side have returned to form with victories over Brentford and the Saints after an eight-game winless run.
They are two points behind fourth-placed Manchester City, who they welcome on 21 December.
Duran's ninth goal of the season and his overall performance earned praised from Emery.
"Fantastic, because he is helping us in everything, scoring goals, and we are very demanding with him tactically. Today he did the work," said the manager.
"The most important thing was how he worked and scoring as well is better for the team."
Duran has made just four starts when taking all competitions into account, with Emery using the 20-year-old carefully at this stage of his career.
Emery added: "We have had to try to stop his passionate moments sometimes but that is something natural, he is young and he wants everything quickly."
Southampton are being cut adrift at the bottom and are eight points from the safety line having lost 12 of their 15 top flight games.
Russell Martin's visitors showed promise, but a soft underbelly cost them in the 24th minute when Taylor Harwood-Bellis failed to deal with a hopeful ball to Duran and the striker raced clear to score.
"I love Taylor and I don't want to criticise him, but what happened can't happen," said Martin.
"Smooth the game out and pass the ball to a team-mate or you defend and clear it and we did neither. The goals we concede are so poor."
Southampton also failed to manage a shot on target and are the lowest scorers in the Premier League with just 11 goals.
"It's madness," said Martin. "We had one where Flynn [Downes] is in the middle of the goal, Cam Archer is in the box.
"I don't know what more I can give to the players to make them believe and that extra spark.
"Other than stop the game and tell players how good they are and what they can go and do, it's just that bit of spark and belief in the final third."
Duran's goal was the highlight of a forgettable game. Villa did not need to be at their best and Southampton lacked the quality to recover from conceding another sloppy goal.
Villa were able to collect only their second clean sheet in the league this season and goalkeeper Emi Martinez was never tested.
The hosts allowed the game to drift in the second half, unable to build on their lead, but they were never in serious danger and Joe Lumley denied John McGinn the chance to make victory more comfortable in injury time.