Video shows scene of crashpublished at 20:16 BST
One passenger, Dr Peter Knapp, describes the collision.
"Some people are spitting out blood," he says.
A major emergency response is under way after a collision between two passenger trains in the Bedford area
Firefighters, police and ambulance crews are at the scene
Passenger Peter Knapp tells BBC News he was in the front carriage of one of the trains: "I felt like I'd been in a bomb explosion"
"It was like a big bang, then people flew from their seats," says passenger Shola Mene
East Midlands Railway says all its services to and from London St Pancras have been suspended for the rest of the day
Rail operator Thameslink says all lines are blocked between Luton and Bedford and urges people not to travel
Transport Secretary Heidi Alexander says she is "deeply concerned" about the reports and is grateful to emergency services at the scene
Edited by Andrew Woodger and Andrew Humphrey
One passenger, Dr Peter Knapp, describes the collision.
"Some people are spitting out blood," he says.
Holly Nichols
in Bedford
Image source, Holly Nichols/BBCShola Mene was on one of the trains this evening.
"It was like a big bang," she says of the collision.
"Then people flew from their seats, the seats were pulling, and then someone just flew across and hit my husband in the face.
"There was a lot of blood. A lot of people had facial injuries."
She added that she did not think the train was going fast, but there was a lot of confusion as to what had happened.

An East Midlands Railway spokesperson , externalsaid: "The 16:40 EMR train from Corby to London St Pancras has been involved in a collision with 15:50 Nottingham [to] London St Pancras, at Bedford South.
"We are currently on the scene and working with Network Rail to assist the emergency services.
"Further updates will be provided as soon as more information is established."
Katy Austin
Transport correspondent
The Rail Accident Investigation Branch (RAIB) has said on X: "A team of RAIB inspectors is on site at the scene of a collision between two trains near Elstow, to start gathering evidence.".
It’s the RAIB’s job to investigate exactly what happened, and come up with recommendations to prevent the same thing happening again.
Dave Calfe, general secretary of the train drivers' union ASLEF, echoed the thoughts of his RMT counterparts.
"We are deeply concerned by reports of a collision between two trains near Bedford," he said.
"Our thoughts at this moment are with all the staff and passengers on board. Thank you to the emergency services for their ongoing work responding to this incident."
Image source, Sam Read/BBCMohammad Yasin, pictured in 2025
Mohammad Yasin, the MP for Bedford, which is close to where the collision took place, has just spoken to BBC News about the incident, saying it is "really, really concerning".
He says there has been a "derailment" and two trains were involved, with emergency services now at the scene.
Yasin adds the incident only took place a short while ago and there is still a lot he doesn't know, but it is a "very serious incident" and there are a number of casualties.
We are waiting for more details before we can make further comment, he adds.
Yasin says the incident took place in an area called Elstow, which is a few miles south of Bedford, while the nearest hospital is "about two miles away".
He is in contact with the police and will share any further information when it comes out, the MP adds.
A National Union of Rail, Maritime and Transport Workers spokesperson said: "We are deeply concerned by reports of a train collision between Bedford and Luton and the serious injuries sustained by on-board train staff and passengers.
"The thoughts of the whole union are with those affected and we continue to monitor the situation."

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Image source, Katy Lewis/BBCTrain information screens at St Albans railway station show services that are affected.
St Albans is south of Luton. Bedford is further north of Luton on the same line.
Image source, Dr Peter KnappBBC reporter Holly Nichols is in Bedford near the scene of the crash."I can see about 30-40 people walking towards us. There are lots of very upset people," she says.
"It is mostly commuters, but a mix of ages.
"Family members are turning up to pick people up," she added.
She could also see police vehicles and a cordon at the site.
Passenger Peter Knapp tells BBC News he was in the front carriage of one of the trains involved in the collision.
"I felt like I'd been in a bomb explosion," he says.
He describes seeing "bloodied faces", people with what appeared to be broken legs, and "smoke everywhere".
Knapp says he "can't sit down because my back hurts so much” but is otherwise "OK".
He says he "must have been very lucky" but "can't imagine what the situation of the driver is".
Knapp is now on the main road "parallel to the train" and describes seeing ambulances, fire engines and police at the scene.
East Midlands Railway services to and from London St Pancras are suspended for the remainder of Friday, the train operator has said following a collision between two passenger trains in Bedfordshire.
Transport Secretary Heidi Alexander says she is "deeply concerned to hear reports of the collision involving two East Midlands Railway passenger trains".
"I’m grateful to emergency services who are on the scene, attending to those affected. We're working quickly with the rail industry and local partners to support passengers," she adds in a post on X.
Image source, Dr Peter KnappThe East of England Ambulance Service has sent "a number of resources" to the scene including an air ambulance, a spokesperson said.
The air ambulance has been spotted on Flightradar24 flying in the area south of Bedford.
A Hazardous Area Response Team has also been sent by the ambulance service and it encouraged people to avoid the area.
Bedfordshire Police has said in a social media post, external that officers are also at the scene of an incident on the railway line, just south of Bedford.
"All lines through the area have been stopped," a spokesperson said.
"Please check your journey before you travel and allow plenty of extra time.
"We are asking people to avoid the area and we will update when we can."
Operator East Midlands Railway says its services are also being affected by the incident.
Trains between London St Pancras and Leicester are being disrupted and are unable to run in or out of London "for the remainder of this evening".
"Passengers are advised not to travel," it said.
British Transport Police is responding to reports of a “collision involving two trains” in the Bedford area, the force says in a statement on social media.
Thameslink reports that all lines are blocked between Luton and Bedford and have been since about 17:30 BST.
Numerous services this evening have been delayed and will likely be cancelled due to the ongoing incident.
Those currently on trains along the line have been told by the rail operator to remain on board and await further information.
A spokesperson for Thameslink told the BBC the emergency services were dealing with an incident and they directed further inquiries to the British Transport Police.
Bedfordshire Fire and Rescue Service has confirmed on social media that it is at the scene of the incident on the railway just south of Bedford.
"Please avoid the area," a spokesperson says.
A spokesperson for rail operator Thameslink is "strongly" urging people not to travel until later today.
"If you cannot delay your journey, please note that you will be severely delayed and will likely need to use an alternative route to reach your destination."
Replacement buses have been requested, they added.