Koukalova (above) was dispatched inside an hour by American Jackson
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A trio of seeds suffered early exits on day one of traditional Wimbledon warm-up, the DFS Classic in Birmingham.
World number 36 and 10th seed, Klara Koukalova, was beaten 6-4 6-1 by American teenager Jamea Jackson.
Slovakian Martina Sucha converted seven out of 19 break points to comfortably dispatch Colombian 11th seed Catalina Castano 6-3 6-1.
American Laura Granville, who was seeded 16th at Edgbaston, then crashed out 6-4 6-4 to China's Zi Yan.
The only seed to survive in the early matches was Swedish number one Sofia Arvidsson, who beat Hungarian counterpart Melinda Czink 7-5 4-6 6-3.
British number four Sarah Borwell beat fellow Briton Melanie South 7-6 3-6 6-3 to also go through.
The top eight seeds in Birmingham have all been awarded second-round byes and will play on Tuesday.
Two-time defending champion and world number four Maria Sharapova heads the field, although she is continuing to struggle with an ankle injury.
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