Leicester head coach Pat Howard on making five changes to the side:
"I said to the guys I was willing to lose this one to do something we have not done before.
"We had to answer our critics and prove to ourselves we are capable of playing a different type of rugby.
"We did not play with enough ambition against Bath and we went to another extreme this time."
Northampton: Reihana; Lamont, Clarke, Quinlan, Cohen; Spencer, Robinson; Smith, Thompson, Barnard; D Browne, Lord; Tupai, Fox, D Browne.
Replacements: Budgen for Barnard (62), Gerard for Lord (68), Lewitt for Tupai (58), Harding for Fox (58).
Not Used: Richmond, Howard, Kydd.
Sin Bin: Spencer (7)
Leicester: Murphy; A Tuilagi, Hipkiss, Vesty, Varndell; Healey, Bemand; White, Chuter, Rowntree; Cullen, Kay; L Deacon, Moody, Corry.
Replacements: Smith for Murphy (41), Gibson for Hipkiss (51), Goode for Healey (55), Buckland for Chuter (41), Holford for L Deacon (9), Jennings for Moody (62), Hamilton for Holford (18).
Sin Bin: Rowntree (7), Holford (78)
Att: 13,493
Referee: Tony Spreadbury (Bristol)