Wigan boss Brian Noble:
"We have to find an answer because one week we are getting Jekyll and one week we are getting Hyde.
"It's frustrating to have some people setting themselves really high standards one week but not living up to them the next.
"I am disappointed that we can't get an element of consistency in our game."
Harlequins: Melling, Wells, Sykes, T Smith, Clubb, Orr, McLinden, Temata, Randall, Mills, Gafa, Hopkins, Hill.
Replacements: Rinaldi, Worrincy, Mbu, Walsh.
Wigan: Ashton, Calderwood, Bailey, Vaealiki, Richards, Barrett, Leuluai, Fielden, Millard, Paleaaesina, Hock, Fletcher, O'Loughlin.
Replacements: Higham, Hansen, O'Carroll, Prescott.