Ballack has not played since limping off against Newcastle
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Chelsea have been rocked by the news that Michael Ballack and Ricardo Carvalho will miss Tuesday's Champions League semi-final against Liverpool.
The Blues lead 1-0 after the first leg but midfielder Ballack is likely to miss the rest of the season after having ankle surgery on Friday.
The 30-year-old picked up the injury in the early stages of Chelsea's goalless draw with Newcastle last weekend.
Defender Carvalho, 28, sustained a knee problem against Bolton on Saturday.
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We lost at Liverpool in the Premiership without Ricardo Carvalho and we go to Anfield again without him
Chelsea boss Jose Mourinho
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Ballack travelled to Munich for his operation, where he was treated by Germany's national team doctor Hans-Wilhelm Muller-Wohlfahrt.
He has scored eight goals for the Blues since joining on a free transfer from Bayern Munich last summer.
Carvalho was injured in the first half against Bolton and Chelsea manager Jose Mourinho said: "He is definitely out.
"He has injured his knee and it is a big blow for us. He has been our best defender this season - it is as simple as that.
"We lost at Liverpool in the Premiership without him and we go to Anfield again without him.