Former Arsenal star Paul Merson believes the England team could be affected because teams like the Gunners are focusing on foreign players.
Monday's 5-1 Premiership win over Crystal Palace marked the first time ever an English club squad was completely foreign.
"I think it's a joke, really, that's my opinion," said Merson.
"You can understand why England are struggling when top clubs like Arsenal have no English players playing."
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You've got to feel for the lads who are 16 and 17 coming through the ranks
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That view was endorsed by players' union boss Gordon Taylor, who attacked Arsenal's David Dein for failing to back Uefa's quota proposals.
"Arsene Wenger has a job to do, so I don't want to be critical of him," said Taylor.
"But this is a worrying pattern for English football. Are our stars of the future getting the opportunities they need?
"What worries me even more though is the attitude of David Dein. Here is a man, a prominent member of the FA's international committee, openly lobbying against Uefa's quota proposals."
Dein has dismissed the European governing body's plan, requiring a minimum of four home-grown players in squads from 2006, rising to eight two years later, as unworkable.
He claims it is almost certain to face a legal challenge for restraint of trade and that the quality of the Premier League would suffer if the ruling was imposed domestically.
But Taylor added: "The one thing the Football Association has got to do is protect the future interests of the game in England.