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Friday, June 25, 1999 Published at 01:50 GMT 02:50 UK Sci/Tech Human cloning: The debate ![]() The continuing ban on human cloning in the UK continues to elicit strong emotional reactions from both scientists and anti-abortionists. BBC News Online invited representatives from both sides of the debate on human cloning to set out their arguments for and against - Dr Simon Best, managing director of Geron Biomed, the commercial arm of the Roslin Institute which cloned Dolly the sheep, and Peter Garrett, Research Director of the anti-abortion campaign group Life.
Therapeutic cloning has the potential to develop treatments for a wide range of degenerative diseases - such as diabetes, Parkinson's, Alzheimer's, hepatitis, liver cirrhosis and cancer - for which none currently exist. In diseases such as these, cells die and/or lose their normal function, and the body loses the ability to replace them. Therapeutic cloning opens up the possibility of providing new populations of healthy cells to replace these.
At the moment, the only way of doing this is to extract them from early stage pre-embryos - typically at the 5-6 day stage. Stem cells were first derived from spare pre-embryos donated following successful in-vitro fertilisation (IVF) procedures. To create cells that will not be rejected by a patient, it is currently necessary to use the nuclear transfer cloning technique that produced Dolly the sheep to make a new pre-embryo from which to derive fresh supplies of the patient's own cells. We now believe that it is appropriate to start research using current techniques to confirm that the potentially enormous therapeutic benefits of this technology can actually be realised in practice. This would not require the culture of embryos beyond the 14-day stage and this has been approved for some time in the UK in the case of IVF treatment. IVF has allowed several thousand families to have healthy children who would not otherwise have been able to do so, and we believe that the same principles should apply in the case of therapeutic cloning given the enormous benefits that may be achieved.
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